If she owned and lived in her home 2 of the last 5 years she can exclude $250,000 from her capital gain on the home sale. Her gain is the net selling income minus the original cost and any capital improvement costs. If her income is low enough she might also escape more of her capital gains tax.
If the home had been previously owned jointly by both your parents, half the cost basis "stepped up" on the death of her husband (the entire cost basis stepped up if they lived in a community property state). This would reduce the capital gain amount.
If my mom's capital tax is zero due to step up basis in community property after her husband's death and the death appraisal value is greater than selling price, does she need to file taxes? No refund or taxes owed for federal and state.
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